The significance of natriuretic peptides in the control of cardiovascular system function has been demonstrated.
Clinical information and imaging procedures are used to diagnose left ventricular dysfunction. The high sensitivity of NT‐proBNP allows also the detection of mild forms of cardiac dysfunction in asymptomatic patients with structural heart disease. When patients are grouped according to their NYHA classification NT‐proBNP levels increase with increasing class numbers and reflect the severity of cardiac impairment. Based on the symptoms, the severity of cardiac insufficiency is classified in stages (New York Heart Association classification I‐IV). due to sudden cardiac death.Ĭhronic cardiac insufficiency is a clinical syndrome caused by impairment of the cardiac pumping function. If the left ventricular dysfunction remains untreated and is progressive, the potential for mortality is high, e.g. Left ventricular dysfunction can occur as a part of coronary heart disease, arterial hypertension, valvular disease, and primary myocardial disease. This assay is further indicated for the risk stratification of patients with acute coronary syndrome and congestive heart failure, and it can also be used for monitoring the treatment in patients with left ventricular dysfunction. The test also aids in the assessment of heart failure severity in patients diagnosed with congestive heart failure. This assay is indicated as an aid in the diagnosis of individuals suspected of having congestive heart failure and detection of mild forms of cardiac dysfunction.
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